Dietary Influences on the Microbiota–Gut–Brain Axis
نویسندگان
چکیده
Over unimaginable expanses of evolutionary time, our gut microbiota have co-evolved with us, creating a symbiotic relationship in which each is utterly dependent upon the other. Far from confined to recesses alimentary tract, engage complex and bi-directional communication their host, far-reaching implications for overall health, wellbeing normal physiological functioning. Amongst such streams, microbiota–gut–brain axis predominates. Numerous mechanisms involve direct effects microbiota, or indirect through release absorption metabolic by-products microbiota. Proposed implicate mitochondrial function, hypothalamus–pituitary–adrenal axis, autonomic, neuro-humeral, entero-endocrine immunomodulatory pathways. Furthermore, dietary composition influences relative abundance species. Recent human-based data reveal that on can occur rapidly, reflect diet at any given although much inter-individual variation pertains. Although most studies macronutrients report associations changes particular species bacteria, broad terms, modern-day animal-based Westernized diets are relatively high fats proteins impoverished fibres. This creates perfect storm within dysbiosis promotes localized inflammation, enhanced wall permeability, increased production lipopolysaccharides, chronic endotoxemia resultant low-grade systemic inflammatory milieu, harbinger dysfunction many illnesses. Research should further focus colony health wellbeing, dysbiotic pathogenic Finally, we revise view seething mass microbes one organ-status, depends. Future guidelines lifestyle strategies integrate advice optimal establishment maintenance healthy other means. what eat, perhaps more importantly, thrive they eat.
منابع مشابه
Dietary Influences on Porcine Postweaning Diarrhoea
The occurrence of diarrhoea in piglets within three to 10 days of weaning (postweaning diarrhoea; PWD) has long been associated with the proliferation of certain serotypes of betahaemolytic Escherichia coli in the proximal small intestine of affected animals (Richards and Fraser, 1961). Many of these E. coli isolates have been found to be enterotoxigenic [ETEC], producing either heat stable tox...
متن کاملDietary influences on serum lipids and lipoproteins.
Substantial data are available to indicate that the diet influences serum levels of cholesterol and lipoproteins. These data are derived from studies in laboratory animals, from epidemiologic studies, and from human investigations. Most research has focused on effects of diet on serum total cholesterol concentrations. In recent years, however, attention has shifted to individual lipoproteins, i...
متن کاملsurvey on the rule of the due & hindering relying on the sheikh ansaris ideas
قاعده مقتضی و مانع در متون فقهی کم و بیش مستند احکام قرار گرفته و مورد مناقشه فقهاء و اصولیین می باشد و مشهور معتقند مقتضی و مانع، قاعده نیست بلکه یکی از مسائل ذیل استصحاب است لذا نگارنده بر آن شد تا پیرامون این قاعده پژوهش جامعی انجام دهد. به عقیده ما مقتضی دارای حیثیت مستقلی است و هر گاه می گوییم مقتضی احراز شد یعنی با ماهیت مستقل خودش محرز گشته و قطعا اقتضاء خود را خواهد داشت مانند نکاح که ...
15 صفحه اولEffects of Dietary Protein on Thyroid Axis Activity
Thyroid hormones (TH) are essential for the normal development and function of every vertebrate. The hypothalamic-pituitary-thyroid (HPT) axis is regulated to maintain euthyroid status. One of the most influential environmental factors that determines HPT axis activity is nutrition. Both food availability and substrate diversity affect thyroid hormone economy. The present paper aims to summariz...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2021
ISSN: ['1661-6596', '1422-0067']
DOI: https://doi.org/10.3390/ijms22073502